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Bruker Corporation topspin software version 3 6 1
Topspin Software Version 3 6 1, supplied by Bruker Corporation, used in various techniques. Bioz Stars score: 99/100, based on 14296 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/topspin+software+3+6+1+version/TopSpin+Software/pmc12269082__mz5c00315_si_001-41-17-16
Average 99 stars, based on 14296 article reviews
topspin software version 3 6 1 - by Bioz Stars, 2026-10
99/100 stars

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Nuclear Magnetic Resonance:

Article Title: Enantiomers of the prion protein degrader SM875: Production and configurational assignment, in silico analysis and in vitro evaluation.
Article Snippet: Prion diseases are rare and fatal neurodegenerative conditions affecting humans and animals caused by the misfolding of the cellular prion protein (PrP).. Recently, the molecule 1-(4-bromophenyl)-1,4,5,7-tetrahydro-4-(4hydroxy-3)-6H-pyrazolo[3,4-b]pyridin-6-one, named SM875, was identified as a promising PrP degrader through a computational approach targeting folding intermediates.. The racemic mixture of SM875 showed biological activity but also exhibited variable toxicity.

Software:

Article Title: Enantiomers of the prion protein degrader SM875: Production and configurational assignment, in silico analysis and in vitro evaluation.
Article Snippet: Prion diseases are rare and fatal neurodegenerative conditions affecting humans and animals caused by the misfolding of the cellular prion protein (PrP).. Recently, the molecule 1-(4-bromophenyl)-1,4,5,7-tetrahydro-4-(4hydroxy-3)-6H-pyrazolo[3,4-b]pyridin-6-one, named SM875, was identified as a promising PrP degrader through a computational approach targeting folding intermediates.. The racemic mixture of SM875 showed biological activity but also exhibited variable toxicity.



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